Framingham 10-Year CVD Risk Calculator

10-year general cardiovascular disease risk per D'Agostino 2008 Circulation. Sex-specific, lab-based.

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How to use this calculator

  • Enter sex, age, TC, HDL, SBP, BP-Tx, smoker, diabetes.
  • Read 10-year general CVD risk + band.
  • Pair with risk-enhancers (FH, hsCRP, CAC, CKD, etc.).

About this calculator

Framingham general CVD risk: 10-year probability of any first CVD event (CHD, stroke, PAD, HF) in adults 30-74 without prior CVD. Source: D'Agostino RB Sr et al., "General cardiovascular risk profile for use in primary care: the Framingham Heart Study." Circulation 2008;117(6):743-53. Cox proportional hazards model, sex-specific coefficients, with treated vs. untreated SBP coefficients separately. NCEP ATP III and ACC/AHA later adopted this for primary prevention decisions. Note: ACC/AHA 2013 introduced "Pooled Cohort Equations" for ASCVD (Goff DC, Circulation 2014;129:S49) — different, more inclusive, 40-79 age range, includes race. This calc is the classic Framingham 2008 model. **Not medical advice — pair with shared decision and risk-enhancing factors.**

Frequently asked

Source of the formula?+
D'Agostino RB Sr et al., Circulation 2008;117:743-53. Coefficients in Table 2 of the paper.
Framingham vs. ACC/AHA Pooled Cohort Equations?+
PCE (Goff 2014) extended Framingham to include race and a wider 40-79 age band; specifically targets hard ASCVD (MI, stroke). Framingham 2008 includes broader CVD (HF, PAD too).
Why log-transform variables?+
Hazard ratios scale multiplicatively with continuous risk factors — log makes the linear predictor additive on the natural scale.
Treated vs. untreated SBP coefficients?+
Treated patients have higher residual risk than untreated patients with the same observed BP — the coefficient adjusts for that.
Risk bands for treatment decisions?+
<5% low, 5-9% borderline, 10-19% intermediate, ≥20% high. ACC/AHA 2018 cholesterol guideline (Grundy, Circulation 2018) uses ASCVD risk; statin recommended at ≥7.5% (intermediate).
Is this medical advice?+
No. Educational. CVD prevention requires individual context + shared decision.

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